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Medication guide

Levocetirizine

Generic name
Levocetirizine
Common brand names
Xyzal
Medication class
Second-generation antihistamine

Overview

Its medication class is Second-generation antihistamine. Common uses include Allergic rhinitis and skin itching. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral tablet/syrup.
Time of day
Usually once daily in the morning.
With food/water
Take with or without food; use 120–240 mL water.
Preparation
Swallow tablets whole.
Safe dose
Use the labeled standard dose (often 1 tablet) unless age-adjusted.
Max dose
Do not exceed one label-defined daily dose and avoid duplicate antihistamines.
Frequency
Once every 24 hours unless label says otherwise.
Other recommendations
Use caution if driving until individualized response to sedation is known.

Common uses

  • Allergic rhinitis and skin itching

Common side effects

  • Sleepiness
  • headache
  • fatigue
  • dry mouth
  • dizziness
  • nausea
  • and occasional abdominal pain

Important warnings

  • Sedation and reduced alertness can occur. Use caution in glaucoma, urinary retention risk, severe kidney impairment, and in the elderly. Avoid co-use with alcohol/CNS depressants or other antihistamines. Do not use beyond label without reassessment if persistent hives or severe allergic breathing symptoms.

General interactions information

Additive sedation with CNS depressants; avoid stacking sedating antihistamines.

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

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