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Medication guide

Cetirizine

Generic name
Cetirizine
Common brand names
Zyrtec
Medication class
Second-generation antihistamine

Overview

Its medication class is Second-generation antihistamine. Common uses include Allergic rhinitis, chronic urticaria, and itching. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral tablet/syrup.
Time of day
Usually once daily in the morning.
With food/water
Take with or without food; use 120–240 mL water.
Preparation
Swallow tablets whole.
Safe dose
Use the labeled standard dose (often 1 tablet) unless age-adjusted.
Max dose
Do not exceed one label-defined daily dose and avoid duplicate antihistamines.
Frequency
Once every 24 hours unless label says otherwise.
Other recommendations
Use caution if driving until individualized response to sedation is known.

Common uses

  • Allergic rhinitis
  • chronic urticaria
  • itching

Common side effects

  • Drowsiness
  • fatigue
  • dry mouth
  • headache
  • dizziness
  • nausea
  • and abdominal discomfort

Important warnings

  • Use with caution if driving or operating machinery until alertness effects are known, especially at higher doses or with alcohol. Avoid if history of severe hypersensitivity to cetirizine/piperazine derivatives. Avoid combining multiple sedating antihistamines. Children and older adults should use lowest effective dose and avoid abrupt discontinuation without advice.

General interactions information

Relatively low interaction burden; avoid concurrent sedatives/alcohol if sleepy

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

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