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Medication guide

Fexofenadine

Generic name
Fexofenadine
Common brand names
Allegra
Medication class
Second-generation antihistamine

Overview

Its medication class is Second-generation antihistamine. Common uses include Allergic rhinitis and hives. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral tablet/syrup.
Time of day
Usually once daily in the morning.
With food/water
Take with or without food; use 120–240 mL water.
Preparation
Swallow tablets whole.
Safe dose
Use the labeled standard dose (often 1 tablet) unless age-adjusted.
Max dose
Do not exceed one label-defined daily dose and avoid duplicate antihistamines.
Frequency
Once every 24 hours unless label says otherwise.
Other recommendations
Use caution if driving until individualized response to sedation is known.

Common uses

  • Allergic rhinitis and hives

Common side effects

  • Headache
  • nausea
  • fatigue
  • dizziness
  • dry mouth
  • and stomach upset

Important warnings

  • Separate from antacids containing aluminum/magnesium and certain supplements/juices that reduce absorption; avoid exceeding maximum daily dose. Do not combine with other antihistamines without clinician direction. Monitor older adults for fatigue or QT-risk with pre-existing heart disease. Seek urgent care for anaphylaxis-like symptoms.

General interactions information

Can interact with antacids/supplements; separate dosing to improve effectiveness.

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

Editorial record

Recorded content review date:

A named medical reviewer and their credentials have not yet been documented for this guide.

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