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Medication guide

Docosanol (10%)

Generic name
Docosanol (10%)
Common brand names
Abreva Cold Sore Cream
Medication class
Topical antiviral (herpes labialis)

Overview

Its medication class is Topical antiviral (herpes labialis). Common uses include Early cold sore symptom shortening. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Editorial correction, September 24, 2026: the imported route label was corrected using the references below. This does not constitute a full medical review of the guide.

Route
Topical cream for cold sores on the face or lips. Do not apply inside the mouth or in or near the eyes.
Time of day
At symptom onset and before bed when sore-throat or oral discomfort occurs.
With food/water
Do not swallow concentrated products unless label allows; sip plain water if needed.
Preparation
Apply thinly or allow to dissolve as directed.
Safe dose
Use smallest amount needed and short-term intervals.
Max dose
Stay within label daily limit; avoid use in young children unless approved.
Frequency
Often every 2–6 hours as needed.
Other recommendations
Avoid alcohol mouth rinses and follow age restrictions.

Common uses

  • Early cold sore symptom shortening

Common side effects

  • Burning
  • itching
  • skin irritation
  • headache
  • and contact dermatitis

Important warnings

  • Use at earliest symptoms. Not a substitute for antiviral therapy in severe recurrent herpes. Avoid if lesions are severe/immunocompromised without clinician guidance. Stop and seek care for worsening lesions, eye involvement, facial swelling, or fever.

General interactions information

Low interactions; avoid mucosal overuse

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

Editorial record

Recorded content review date:

A named medical reviewer and their credentials have not yet been documented for this guide.

Editorial standards and corrections
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