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Medication guide

Simethicone

Generic name
Simethicone
Common brand names
Gas-X, Phazyme
Medication class
Antiflatulent

Overview

Its medication class is Antiflatulent. Common uses include Gas and bloating. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Editorial correction, September 24, 2026: the imported route label was corrected using the references below. This does not constitute a full medical review of the guide.

Route
Oral tablets, chewable tablets, capsules, or liquid, depending on the product. Simethicone is used for gas symptoms.
Time of day
Use at start of loose stool episode and as per label if stools continue.
With food/water
Use with water and small frequent fluids.
Preparation
Swallow tablets at first diarrhea episode and after each additional stool as labeled.
Safe dose
Keep to initial dose plus labeled maintenance doses only.
Max dose
Do not exceed OTC daily cap.
Frequency
Interval-based dosing; never stack multiple antidiarrheals.
Other recommendations
Seek urgent care for blood, fever, severe dehydration, or infant/elderly dehydration signs.

Common uses

  • Gas and bloating

Common side effects

  • Nausea
  • bloating
  • mild abdominal pain
  • headache
  • and diarrhea

Important warnings

  • Generally low risk, but persistent pain, fever, vomiting, bloating, or inability to pass stool/absent bowel sounds needs urgent assessment. Not for undiagnosed abdominal emergencies; use OTC care only for temporary gas relief.

General interactions information

Minimal systemic interactions; usually compatible with other GI meds

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

Editorial record

Recorded content review date:

A named medical reviewer and their credentials have not yet been documented for this guide.

Editorial standards and corrections
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