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Medication guide

Pseudoephedrine

Generic name
Pseudoephedrine
Common brand names
Sudafed (Behind-the-Counter/OTC in some regions)
Medication class
Sympathomimetic oral decongestant

Overview

Its medication class is Sympathomimetic oral decongestant. Common uses include Nasal congestion from URI/allergic causes. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral tablet/capsule.
Time of day
Morning/early afternoon to reduce insomnia.
With food/water
120–240 mL water; food reduces GI upset.
Preparation
Take immediately after meal for comfort unless label differs.
Safe dose
Use the lowest effective dose for symptom duration.
Max dose
Use only labeled daily maximum and avoid multiple products with same stimulant.
Frequency
Every 4–12 hours depending agent/dosing strength.
Other recommendations
Monitor blood pressure and pulse; avoid if instructed by clinician.

Common uses

  • Nasal congestion from URI/allergic causes

Common side effects

  • Palpitations
  • jitteriness
  • insomnia
  • nervousness
  • headache
  • elevated blood pressure
  • urinary retention
  • and dizziness

Important warnings

  • Contraindicated in uncontrolled hypertension, unstable coronary disease, severe glaucoma, and severe hyperthyroidism. Use caution in pregnancy, diabetes, and urinary retention. Avoid with MAOIs and within 2 weeks after discontinuing MAOIs. Stop and seek urgent care for chest pain, severe agitation, palpitations, fainting, dyspnea, or severe headache.

General interactions information

Additive with stimulants, some antidepressants/MAOIs, and cold preparations

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

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