Public health libraryEducational information. No account needed.

Medication guide

Naproxen Sodium

Generic name
Naproxen Sodium
Common brand names
Aleve, Midol Extended Relief
Medication class
NSAID

Overview

Its medication class is NSAID. Common uses include Headache, muscle pain, menstrual cramps, and general aches and pain relief. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral tablet/capsule/liquid
Time of day
Use when needed for pain or fever; space doses consistently for sustained symptoms.
With food/water
120–240 mL water; food may reduce nausea.
Preparation
Use only label-strength forms for adults/children and swallow tablets with water.
Safe dose
Start at the lowest effective dose listed on the product label.
Max dose
Do not exceed the product label daily amount; avoid combining same-class ingredients.
Frequency
Every 4–8 hours as directed, usually no sooner than label interval.
Other recommendations
Use labels to separate from other acetaminophen/NSAID products and alcohol-containing medicines.

Common uses

  • Headache
  • muscle pain
  • menstrual cramps
  • general aches and pain relief

Common side effects

  • Stomach pain
  • nausea
  • vomiting
  • constipation or diarrhea
  • headache
  • dizziness
  • gas
  • fluid retention
  • abdominal bloating
  • and rash

Important warnings

  • Avoid in peptic ulcer disease, severe renal/hepatic impairment, prior GI bleed, aspirin-sensitive asthma, and late pregnancy. Avoid concurrent use of other NSAIDs or corticosteroids without clinician guidance. Risk rises with high doses and long use. Stop and evaluate if persistent abdominal pain, vomiting, blood in stool, confusion, or swelling occurs.

General interactions information

Avoid combining with other NSAIDs, aspirin, blood thinners, and some blood-pressure medicines.

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

Editorial record

Recorded content review date:

A named medical reviewer and their credentials have not yet been documented for this guide.

Editorial standards and corrections
Browse all medications →