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Medication guide

Chlorpheniramine

Generic name
Chlorpheniramine
Common brand names
Chlor-Trimeton
Medication class
First-generation antihistamine

Overview

Its medication class is First-generation antihistamine. Common uses include Allergic rhinitis, runny nose, and sneezing. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral tablet/liquid.
Time of day
Best taken in the evening/bedtime; avoid driving after dosing.
With food/water
Water with or without light food, esp. if stomach upset.
Preparation
Take only one labeled product at a time.
Safe dose
Use the lowest dose for age and indication.
Max dose
Do not exceed label daily cap.
Frequency
Every 4–8 hours when needed unless adverse drowsiness occurs.
Other recommendations
Avoid alcohol and other sedatives; do not combine with sleep aids without guidance.

Common uses

  • Allergic rhinitis
  • runny nose
  • sneezing

Common side effects

  • Sleepiness
  • dry mouth
  • constipation
  • blurred vision
  • dizziness
  • headache
  • nausea
  • and urinary retention

Important warnings

  • Avoid use in narrow-angle glaucoma, urinary retention, severe constipation/ileus, and when sedation must be avoided. Do not combine with sedatives, opioids, or other first-generation antihistamines. In children, dose carefully by age and weight; seek care for severe confusion, urinary retention, or breathing difficulty.

General interactions information

Avoid combining with other sedating antihistamines or alcohol.

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

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