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Medication guide

Bismuth Subsalicylate

Generic name
Bismuth Subsalicylate
Common brand names
Pepto-Bismol, Kaopectate
Medication class
Anti-diarrheal/gastrointestinal protective agent

Overview

Its medication class is Anti-diarrheal/gastrointestinal protective agent. Common uses include Nausea, diarrhea, indigestion, and traveler’s GI upset. Product forms and labels can differ, so follow the specific package instructions and ask a pharmacist or qualified healthcare professional about individual questions.

How to Take it

Route
Oral antidiarrheal.
Time of day
Use at start of loose stool episode and as per label if stools continue.
With food/water
Use with water and small frequent fluids.
Preparation
Swallow tablets at first diarrhea episode and after each additional stool as labeled.
Safe dose
Keep to initial dose plus labeled maintenance doses only.
Max dose
Do not exceed OTC daily cap.
Frequency
Interval-based dosing; never stack multiple antidiarrheals.
Other recommendations
Seek urgent care for blood, fever, severe dehydration, or infant/elderly dehydration signs.

Common uses

  • Nausea
  • diarrhea
  • indigestion
  • traveler’s GI upset

Common side effects

  • Nausea
  • constipation or diarrhea
  • abdominal pain
  • black stool
  • black tongue
  • and rash

Important warnings

  • Contains salicylate-like effects; avoid in aspirin allergy, active bleeding, severe renal/hepatic failure, and pediatric viral illness. Do not use prolonged high-dose therapy. Seek care for melena, severe abdominal pain, tinnitus, persistent vomiting, or confusion.

General interactions information

Additive salicylate exposure with aspirin/NSAIDs; caution with anticoagulants

Sources / references

These references offer further reading. A source link does not establish that a clinician has reviewed every statement in this guide.

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